Identification and Management Implications of <i>Fusobacterium Nucleatum </i>Pylephlebitis

نویسندگان

چکیده

Suppurativethrombophlebitis of the portal vein, or pylephlebitis, is a rare infectious manifestation. Only few casesresulting from Fusobacterium species have been reported, demonstratingthe disease that in some ways analogous to Lemierre’s syndrome, orsuppurative thrombophlebitis internal jugular vein. Of these, Fusobacteriumnucleatum represents an important subtype with unique colon cancer risk.With high mortality rates up 32% being described past, promptidentification and treatment pylephlebitis necessary avoid pooroutcomes this condition, including complications such as intestinalischemia hypertension. This condition typically presents alongsidebacteremia, for which antibiotic therapy targets anaerobic organismsof oral intestinal mucosa, well Streptococcus species. The useof anticoagulation supported by limited data,which shows potential benefit preventing worsening thrombosis liveratrophy. Here we present case F. nucleatum pylophlebitis whopresented related bacteremia liver abscess after dental infection,and treated coverage antibiotics amoxicillinclavulanate until resolution his hepatic anticoagulationwith apixaban total 6 months.

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ژورنال

عنوان ژورنال: American Journal of Infectious Diseases

سال: 2022

ISSN: ['1553-6203', '1558-6340']

DOI: https://doi.org/10.3844/ajidsp.2022.49.53